Neuromics' Customers

How They Find Us and What they Buy

Trust is hard to maintain and easily lost. It is important to us that our customers can find us and the products required to meet their research needs.

In order to nurture trust, we follow up with each and every customer to make sure they are happy with their Neuromics' experience. We include the opportunity for them to formally rate this experience @ https://birdeye.com/neuromics-186498936.

We plan on rolling out a new website. Our goal is to make it even easier for customers to find us and present content in a way that aligns with customers' needs. This includes making sure content is configured in a way that works on all platforms used including mobile devices.

As part of the process, we recently surveyed users for areas of research, platforms used, how they find companies like ours and what the purchase. Here're rollups of some of the results.

Our customers most frequently purchase Antibodies and Markers. Cells and Cell-Based Assays are increasingly important, We plan on making it easier for users to find related protocols, publications, data and alternative product options.

Trust, for us, includes the ability for our customers to find the correct solutions and if they prove not to work, offer fixes or full refunds. As in the past, we will be posting updates, publications and customer generated data here.

3-D Tissue Models Made Easy

3 Steps to an in vivo Like Assay
We provide both CollaGel Hydrogels with different stiffness options and ready made 3-D Human Tissue Models.

 Building these models can be done in 3 easy steps:

• Step 1: Thaw our CollaGel Hydrogel solution 
• Step 2: Add your cell suspensions 
• Step 3: Watch it gel

HUVECS intergrated into 3-D CollaGel environment.

Due to the way in which it gels, our Collagel Hydrogel is well suited to Bio Printing models.

I will be posting more data as it becomes available.

Check Out Our 3D Human Skin Tissue Model

In vivo Like Model for Studying Skin Diseases/Irritants

I am pleased to announce this new addition to our Cell Based Assay offerings.

3D Human Skin Tissue Model

Cross section of Human Skin Model

The model includes precultured tissue in our engineered and tissue/cell specific Collagel-Hydrogels.

Our 3D human skin model is manufactured in a GMP lab. The model is engineered from multilayered, differentiated epidermal cells. The tissue is provided cultured in inserts using serum free media. The model mimics human skin. It provides an in vivo like environment for studying dermal related diseases and cancers. It is also excellent for skin toxicology and irritancy assays.

Check all our  3D Models:

Name	Applications	Size	Price
Human Blood Brain Barrier Model	In vivo Like Assays	6 wells 12 well 24 well	$1,780 $2,600 $3,625
3D HUVEC Model	In vivo Like Assays	6 well 12 well 24 Well	$1,269 $1,399 $1,539
3-D Human Skin Tissue Model	In vivo Like Assays	6 well 12 well 24 Well	$1,269 $1,399 $1,539

Questions? Contact me directly-Pete Shuster, CEO and Owner, 612-801-1007 or pshuster@neuromics.com.

Ready to Use Blood Brain Barrier Model (BBB)

6, 12 and 24 Well Options

We are pleased to introduce our BBB Model. It is designed to provide more in vivo like data for your drug discovery and toxicology assays.

Our model mimic transport properties of the BBB due to the formation of tight junctions, higher expression of specific carriers, or great cell viability. The model includes brain endothelial cells with pericytes and astrocytes layered in an insert. This model improves endothelial cell polarization and enhance the formation of tight junctions, provide better endothelial cell-to-cell contact that is important for barrier development, and prevent the dilution of secreted neurotrophic factors, and these conditions collectively led to the development of an in vitro model that can truly mimic the BBB.

Diagram of BBB Model Transporters

Our Protocol includes methods for Drug Penetration Asays. 

Transport of a molecule (blue) through 3D Human BBB Model in a luminal to basal direction 

Calculation of apparent permeability (Papp in cm/min)

Apparent permeability coefficient Papp (in cm/min) based on the Fick's law can be calculated according to the following equation:

V_A: volume of abluminal chamber (cm³)

A: membrane surface area (1.12 cm²)

[C]_L: initial luminal tracer concentration (ng/ml)

[C]_A : abluminal tracer concentration (ng/ml) t : time of experiment (min)

 Our goal is to provide you better data...at a lower cost.

3-D Cell Based Assay Solutions

We want to help our customers, collaborators and friends bring their cell based assays to life! Neuromics began offering solutions in early 2011. We have extended our reach with our 3D Nanofibers. These 3-D environments are more biologically realistic leading to:
•more effective biomedical research.

•earlier breakthroughs.

•faster and cheaper time to market for drug development.

•improved stem cell expansion rates.

Here's a video showing green neurosphere (brain cancer cells)  migrating along our nanofibers aligned in the vertical direction. This enables cancer researchers to see cancer in ways never before possible!

Find more videos like this on TechLounge

I will update you as data and related publications become avaialable using these solutions.