Monday, July 22, 2019

Thursday, July 11, 2019

Rodent Cortical Astroglia

Controls for iPSC Derived Astroglia
We have been providing Neuroscientists rodent neurons and astroglia for many years. As a result, they have been frequently referenced in publications.

Here's a recent publications. In this study. the authors use our rat atsroglia as controls to determine homogeneity of iPSC derived cells.

P. Ni, H. Noh, Z. Shao, Q. Zhu, Y. Guan, J.J. Park, F. Arif, J.M. Park, C. Abani, C. Beaudreault, J.S. Park, E. Berry, A. Moghadam, P. Stanton, J.N. Hutchinson, B. Andrews, C. Faux, J. Parnevelas, L.M. Eisenberg, K. Park, V.Y. Bolshakov, S. Chung. (2019). Large-Scale Generation and Characterization of Homogeneous Populations of Migratory Cortical Interneurons from Human Pluripotent Stem Cells. Molecular Therapy-Methods & Clinical Development, 13:414-430. doi: 10.1016/j.omtm.2019.04.002.

Figure: CDP Treatment Enhances Migratory, Morphological, and Electrophysical Maturation (A) Analysis scheme for migration, arborization, and electrophysiology of cINs. (B) CDP treatment significantly increased the migration of generated iPSC cINs. cIN organoids were embedded in a Geltrex matrix at 9 weeks of differentiation with or without CDP treatment and analyzed for migration 7 days after embedding. White scale bars, 200 μm; yellow scale bars, 100 μm.

Need Cells? Just ask us. Rose Ludescher, Manager of Customer Satisfaction, or 866-350-1500.

Sunday, July 07, 2019

Potent and Proven TUJ-1 Markers

Referenced in Over 50 Publications
Tuj-1 is a key marker for neurogenesis. It can be detected in immature neurons and persists throughout the adulthood. We have 2 options both are widely used and frequently published.
Tuj-1 Chicken Polyclonal
Tuj-1 Mouse Monoclonal
Figure: A-B Representative confocal images of tdTomato+/Myosin7a+ hair cells (asterisks and dashed lines) from early and late tracing associated with Tuj1+ neurites (arrowheads in orthogonal views, n = 127 cells from 3 mice for early tracing and 73 cells from 9 mice for late tracing). Published: July 1, 2019

We have great markers for studying neurogenesis.