Friday, August 28, 2015

Small Molecules/Peptides for Pain Researchers

Agonists, Antagonists, Inhibitors and Ligands

The roots of Neuromics is providing solutions for the study of nociceptive and neuropathic pain. Our tools are widely used and frequently published. We are pleased to bring you these small molecules designed to help you better understand the roots of pain and potential therapies.

Figure: Infarct volume after 3 days of reperfusion in the ipsilateral cortex and CP complex in male rats treated with vehicle saline (n=15) or 1 mg/kg per hour BRL 52537 (n=15) started at onset of reperfusion and continued for 22 hours (male-vehicle n=15; male-BRL n=15; mean±SEM). P<.0.05. Related Pub.

Name
Catalog #
Type
Size
Price
187-10
Agonist
10 mg
50 mg
$165
$665
323-10
Antagonist
10 mg
50 mg
$319
$1,319
1224-10
Modulator
10 mg
50 mg
$99
$299
1062-10
Agonist
10 mg
$299
1116-10
Modulator
10 mg
50 mg
$119
$449
3661-10
Antagonist
10 mg
50 mg
$183
$795
699-10
Ligand
10 mg
1 mg
$159
$609
1560-1
Antagonist
1 mg
$135
898-2
Antagonist
2 mg
$179
1055-5
Agonist
5 mg
$139
1056-5
Agonist
5 mg
$139
1480-10
Agonist
10 mg
10 mg
$229
$929
0754-10
Agonist
10 mg
10 mg
$199
$809
910-1
Inhibitor
1 mg
$179
1198-1
Inhibitor
1 mg
$195


Questions? Do not hesitate to contact me @ pshuster@neuromics.com or 612-801-1007. Thank you! Pete Shuster, CEO and Owner, Neuromics.

Wednesday, August 26, 2015

Take Your Neuromics' Brain on an Adventure

Grand Prize is 500 USD!


Have fun. We can't wait to see your ideas.
#brainadventure

Friday, August 14, 2015

Have Brain; Will Travel

Join the Adventure and You Could Win 500 USD
Contest begins September 2015. Monthly winners receive 100 USD. Contest will run for 6 months. Grand prize is 500 USD.
Join Neuromics on our‪#‎BrainAdventure‬ to see all the interesting and unique locations the brain ventures. Starting this September, with all orders, you will receive a Neuromics brain keychain. Take a creative picture or short video of the Neuromics Brain Keychain and tweet it @Neuromics, post it on Neuromics Facebook or LinkedIn Page and be entered in our contest. In the meantime, if you want to join the contest, e-mail rose@neuromics.com and she will mail you your brain.

Wednesday, August 12, 2015

Medical Marijuana Research

What we are learning.

I have reported here Medical Marijuana research and its therapeutic value for treating pain. The specifics posts feature publications that reference use of our Pain and Inflammation Research Markers. These include: J. Desroches, J.-F. Bouchard, L. Gendron, P. Beaulieu. Involvement of cannabinoid receptors in peripheral and spinal morphine analgesia ☆ Neuroscience, Volume 261, 7 March 2014, Pages 23–42.http://dx.doi.org/10.1016/j.neuroscience.2013.12.030.
Iryna A. Khasabova,Sergey Khasabov, Justin Paz, Catherine Harding-Rose, Donald A. Simone, and Virginia S. Seybold. Cannabinoid Type-1 Receptor Reduces Pain and Neurotoxicity Produced by Chemotherapy. The Journal of Neuroscience, 16 May 2012, 32(20): 7091-7101; doi: 10.1523/​JNEUROSCI.0403-12.2012

Here researchers study the impact of Marijuana on memory impairment using our one of our 5-HT Serotonin AntibodiesXavier Viñals, Estefanía Moreno, Laurence Lanfumey, Arnau Cordomí, Antoni Pastor, Rafael de La Torre, Paola Gasperini, Gemma Navarro, Lesley A. Howell, Leonardo Pardo, Carmen Lluís, Enric I. Canela, Peter J. McCormick, Rafael Maldonado, Patricia Robledo. Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors. Published: July 9, 2015DOI: 10.1371/journal.pbio.1002194.
Impact on Memory: Activation of cannabinoid CB1 receptors (CB1R) by delta9-tetrahydrocannabinol (THC) produces a variety of negative effects with major consequences in cannabis users that constitute important drawbacks for the use of cannabinoids as therapeutic agents. For this reason, there is a tremendous medical interest in harnessing the beneficial effects of THC. Behavioral studies carried out in mice lacking 5-HT2A receptors (5-HT2AR) revealed a remarkable 5-HT2AR-dependent dissociation in the beneficial antinociceptive effects of THC and its detrimental amnesic properties We found that specific effects of THC such as memory deficits, anxiolytic-like effects, and social interaction are under the control of 5-HT2AR, but its acute hypolocomotor, hypothermic, anxiogenic, and antinociceptive effects are not. In biochemical studies, we show that CB1R and 5-HT2AR form heteromers that are expressed and functionally active in specific brain regions involved in memory impairment. Remarkably, our functional data shows that costimulation of both receptors by agonists reduces cell signaling, antagonist binding to one receptor blocks signaling of the interacting receptor, and heteromer formation leads to a switch in G-protein coupling for 5-HT2AR from Gq to Gi proteins. Synthetic peptides with the sequence of transmembrane helices 5 and 6 of CB1R, fused to a cell-penetrating peptide, were able to disrupt receptor heteromerization in vivo, leading to a selective abrogation of memory impairments caused by exposure to THC. These data reveal a novel molecular mechanism for the functional interaction between CB1R and 5-HT2AR mediating cognitive impairment. CB1R-5-HT2AR heteromers are thus good targets to dissociate the cognitive deficits induced by THC from its beneficial antinociceptive properties. 



Figures: 5-HT2AR and CB1R form heteromers in transfected cells. In (A), BRET saturation experiments were performed in HEK-293T cells transfected with 0.025 μg of 5-HT2AR-Rluc cDNA and increasing amounts of CB1R-YFP cDNA (0.05 μg to 1.5 μg, black curve), with 0.5 μg of dopamine D1R-Rluc cDNA and increasing amounts of CB1R-YFP cDNA (0.5 μg to 6 μg, yellow line), or with 0.025 μg of 5-HT2AR-Rluc cDNA and increasing amounts of adenosine A1R-YFP cDNA (0.05 μg to 1.5 μg, red line). The relative amount of BRET is given as a function of 100 x the ratio between the fluorescence of the acceptor (YFP) and the luciferase activity of the donor (Rluc). BRET is expressed as milli BRET units (mBU) and is given as the mean ± standard deviation (SD) of 3–6 experiments grouped as a function of the amount of BRET acceptor. In (B), a schematic representation of fluorescence complementation experiments is depicted in the left panel showing that fluorescence only appears after the YFP Venus hemiprotein complementation due to the proximity of two receptors fused to hemi-YFP Venus proteins (cYFP or nYFP). In the right panel, fluorescence at 530 nm was detected in HEK-293T cells transfected with different amounts of cDNA corresponding to both 5-HT2AR-cYFP and CB1R-nYFP (equal amount for each construct), but not in negative controls in which cells were transfected with cDNA corresponding to 5-HT2AR-cYFP and the noninteracting adenosine A1 receptor-nYFP or CB1R-nYFP and the noninteracting dopamine D1 receptor-cYFP. One-way ANOVA followed by a Dunnett’s multiple comparison test showed a significant fluorescence over basal values in HEK-293T cells (** p< 0.01, *** p< 0.001). In (C), PLAs were performed in HEK-293T cells expressing CB1R and 5-HT2AR. Confocal microscopy images (superimposed sections) are shown in which heteromers appear as green spots. In all cases, cell nuclei were stained with DAPI (blue). Scale bars = 20 μm. In (D), PLAs were performed in nontransfected HEK-293T cells, cells transiently transfected with 0.5 μg of CB1R or 5-HT2AR cDNA (negative controls, white columns), or with increasing amounts of CB1R and 5-HT2AR cDNA (black columns). In each case, the ratio between the number of green spots and the number of cells showing spots (ratio r) was calculated. One-way ANOVA followed by a Dunnett’s multiple comparison test showed a significant PLA staining over nontranfected cells (*** p <; 0.001). doi:10.1371/journal.pbio.1002194.g004

Yes, memory impairment must be considered as a side effect of Medical Marijuana, I am confident there are human subjects that would volunteer for cognition studies to get a clearer picture of the short and long term impact on users.

Saturday, August 08, 2015

New Human Brain Microvascular Cells

HBMECS for BBB Researchers

I am pleased by the growing positive response to our Human Endothelial Cells offerings. Our Human Brain Microvascular Endothelial Cells have, far and away, been the most popular. We want to make it easier for you to "buy and try" We are offering them for only 699 USD/500,000 Cells through Aug. 31st, 2015. Note: customers have passaged these cells up to 15 X.

Image: Human Brain Microvascular Endothelial Cells in Culture.
Questions? Please contact me: pshuster@neuromics.com or 612-801-1007.

Monday, August 03, 2015

Gene Expression-Have it Your Way

From Delivery to Stable Expression
Neuromics has a successful track record of helping our clients delivery siRNA, miRNA, Plasmids and other oligos in vitro and in vivo with our Transfection Kits...But my vision with our cell based assay solutions has always been to provide engineered cells and plasmids modified to study your genes of interest. I am pleased to announce we are working with Smart Cell /B-MoGen Technologies to make this happen. We now can provide:
Gene Transfer and Expression Products Leveraging the Sleeping Beauty Technology:

Images: B-MoGen Transposon exhibiting stable expression of five fluorescent genes
Advantages of Sleeping Beauty Transposon System:
· Delivery method is time and cost effective compared to lentiviral delivery.
· Increased cargo-capacity when compared to lentiviral delivery.
· Safest insertion profile of all gene transfer methods.
· Commonly integrated as a single copy.
Custom vector design and assembly, including multi-gene (up to 6) vectors.
We are in the process of formulating standard offerings. In the meantime, I am positioned to offer favorable pricing and terms to early adopters of our Sleeping Beauty Solutions. Please contact me directly pshuster@neuromics.com or 612-801-1007. We can together determine your needs and desired outcomes and provide a statement of work with pricing, project milestones and delivery.

Tuesday, July 21, 2015

Neuropeptides and Stress

Neuropeptides Antagonists, Stress and Alcohol Seeking

Select Neuropeptides can help moderate stress and related Alcohol seeking behaviors. The authors of this study reference use of our ppENK and proDYN Neuropeptides: J.R. Schank,B.S. Nelson,R. Damadzic,J.D. Tapocik,M. Yao,C.E. King,K.E. Rowe,K. Cheng,K.C. Rice,M. Heili. Neurokinin-1 receptor antagonism attenuates neuronal activity triggered by stress-induced reinstatement of alcohol seeking. doi:10.1016/j.neuropharm.2015.07.009.

Image: Mouse striatum stained with D2 cell marker Enkephalin (RA14124) in green and with neuronal marker NeuN in red courtesy of Dr Heike Rebholz of City College of New York.

Our Pain/Inflammation Antibodies are widely used and frequently referenced in studies of stress and the intersection between stress and pain.

Monday, July 13, 2015

Apoptosis and Neurodegeneration

Towards the Development of Disease Specific Assays
Neurodegenerative diseases are becoming increasingly prevalent, especially in the Western societies, with larger percentage of members living to an older age. They have to be seen not only as a health problem, but since they are care-intensive, they also carry a significant economic burden.

Apoptotic pathways are induced in many of these diseases and are key culprits in disease progression.
Figure: Schematic representation of apoptotic pathways. Apoptosis triggered by internal (intrinsic) or external (extrinsic) stress signals that is activated by binding of ligands (e.g. FasL, APO-2L, TRAIL, TNF) to cell surface receptors (e.g. Fas, DR4, DR5, TNF-R1). The intrinsic apoptosis pathway might be triggered by p53 upon DNA damage following exposure to cellular stress. In the intrinsic pathway, death signal reaches mitochondria, leading to release of cytochrome c, which can binds to Apaf1. The cytochrome c/Apaf1 make a complex with pro-caspase-9 (in the presence of dATP), activates caspase-9, which promotes caspase-3 activation, eventually leading to cell death. The extrinsic pathway is initiated through the stimulation of the members of tumor necrosis factor receptor (TNF-R) family (transmembrane death receptors) by their respective ligands. These receptors activate pro-caspases-8, -10 by recruiting the endogenous adaptor protein FADD. Procaspase-8, -10 cleave themselves to form activated caspase-8 or -10. Ultimately, effector enzymes such as caspase-3, -6, -7 are activated in this cascade to mediate apoptosis. Likewise, there can be cross-talk between the intrinsic and extrinsic pathways. For example caspase-8 may cleave Bid to form tBid that is a strong activator of the intrinsic/mitochondrial apoptotic pathway. The intrinsic pathway is usually activated by the recruitment of BAX and BAK to outer mitochondrial membrane, causing cytochrome c release formation of apoptosome and subsequent activation of caspase-9. Activated caspase-9 proteolytically activates caspases-3, -6, and -7. Moreover, some of the effector caspases also can activate caspase-8, forming a positive amplification loop. doi:10.1016/j.pneurobio.2013.10.004.

Working with the Apoptosis Experts at Immunochemistry Technologies and Human Astroglial-Neuron Biosensors Experts at ArunA Biomedical, we plan on  developing disease specific assays. Here's a map of the general process.
We welcome feedback and input on your interests. You can email rose@neuromics.com. We will continue to post updates on exciting new developments.


Tuesday, June 30, 2015

Save 100 USD on our hN2™ Primary Neurons

Potent, Pure and Easy to Culture

Assay data continues to roll in. I am pleased by the high lot to lot consistencies of our hN2 Primary Human Neurons resulting in data reproducibility. Here're an examples of outgrowth/tox assays: In conjunction with Molecular Devices' ImageeXpress HCI platform, hN2 differentiated neuronal cells can be used to evaluate potential toxic effects of test compounds on nuerite outgrowth through visualizing cells stained with β-lll tubulin.

Figure: Dose response curves for the effect of neurotoxic agents on neurite outgrowth. hN2™ cells were cultured in the presence of cytotoxic compounds for 72h, stained for β-lll tubulin, imaged with the ImageeXpress and analyzed for neurite outgrowth.

I am always available for product related issues and questions. I cam be reached at direct phone: 612-801-1007 and pshuster@neuromics.com. Pete Shuster, CEO and Owner, Neuromics.

Wednesday, June 24, 2015

Save 100 USD on Our New Cardiomyocytes

Potent, Pure and Easy to Culture

I am pleased to announce the addition of Human Cardiomyocytes to our Stem and Cell Based Assay Solutions.

Image: Human Cardiomyocyte culture.

These cells are optimized to provide addition options for in-vitro testing of drug to drug candidate toxicities allowing researchers to rule out the ineffective and potentially toxic small molecules/compounds early in the process.

I want to make it easy for you to buy and try. If you are not delighted with your results, I will replace free of charge or refund your purchase. Please also note the select positive feedback on our other primary and stem cells:
We recently used the hMSCs derived from Umbilical Cord Blood. Their performance was nothing less than excellent. We were highly impressed with their morphology and their doubling rate. In addition the cells respond very well to accutase and maintain their performance after passaging. We highly recommend this cell line. Rodney Nash, Ph.D, Georgia State University.
Combined Hippocampus, Cortex, and Ventricular Neurons: "I got 10 million cells total after extraction from the tissue. At Day 4 they all developed long axons. Thank you so much for the replacement." Dr. Lidia Gardner, University of Tennessee HSC.
Neuromics always provides excellent products and the best customer service. I highly recommend this company's antibodies and neuronal cultures. Kirsten Raehal, Purdue Pharma

I am always available for product related issues and questions. I cam be reached at direct phone: 612-801-1007 and pshuster@neuromics.com. Pete Shuster, CEO and Owner, Neuromics.

Monday, June 22, 2015

Voices of our Customers

Your Feedback Matters-A lot

Our follow up processes include actively engaging users of our solutions for feedback and input. This includes Rose Ludescher, Manager of Customer Satisfaction, calling or sending e-mails to each user within 3 weeks of shipment. At the core is our product rating website. If users identify products related issues, we replace them or refund their purchases.

We want to hear from you...the good, the bad and the ugly. We welcome opportunities to fix issues.

We are always pleased when customers share data with us. Here's a recent example.
Image: Mouse striatum stained with D2 cell marker Enkephalin (RA14124) in green and with neuronal marker NeuN in red courtesy of Dr Heike Rebholz of City College of New York.

We are always delighted when we discover our solutions reference in Customer Publications. We try and post all of these to our website. We also post many here in recognition of our customers' research.

For all customers that share data or testimonials, we provide gift cards. It our way of saying thank you, because your feedback matters!

Monday, June 15, 2015

Network vs Isolated Bursting in Motor Neurons

Motor Neurons and MEA
Dysregulated bursting is at the root of many motor neuron/neuromuscular junction disease. ArunA Biomedical teaming with Axion Biosystems have generated relevant bursting data from our Mouse Motor Neurons cultured on Axion-Bioystem's Maestro MEA.


Figure: Mouse Motor Neuron Network Modulation by Bicuculline-ckeck out the entire presentation to learn more: GFP+ Motor Neurons: Development and in-vitro Functional Assessment on Microelectrode Arrays
Protocol User's Guide for Culturing Motor Neuron on MEA(pdf - 679Kb)
ArunA Biomedical's/Neuromic's Mouse Motor Neurons on Axion Biosystem's MEA
Save on Mouse Motor Neuron Kits Through June 30th, 2015
NameCatalog #TypeSpeciesApplicationsSizePrice
Motor Neurons-GFP+ Quick Start Kit mMN7205.QS Primary Neurons M Cell Assays 750,000 $349
Motor Neurons-GFP+ HTS Kit mMN7205-HTS Primary Neurons M Cell Assays 4 X 750,000 $989
GDNF (Human, Mouse) PR27022-2 Protein H; M 2 ug
10 ug
$108
$205
AB2™ Basal Neural Medium AB27011.3 Cell Growth Media H; M Cell Assays 500 ml $69
We will continue providing you content we believe important. Should you have questions, do not hesitate to contact us. Thank you and we stand ready to serve you and your team.

Pete Shuster-CEO and Owner, Neuromics, 612-801-1007, pshuster@neuromics.com

Wednesday, June 10, 2015

MEA and Motor Neurons

Plating Densities of Motor Neurons Matter!

I wanted to share some of the tips and data shared during the ArunA Biomedical's/Axion Biosystem's Webinar on MEA and our Mouse Motor Neurons

Plating Cells on Axion's MEA
  • Surface Coating PEI-laminin for adhesion and uniform monolayer development 
  • Dotting Constrains cells to the array 
  • Requires fewer cells per well 
  • Media changes every 2-3 days
  • Variations on Cell Density
Detailed Protocol for Culturing Motor Neurons on MEA
Different Plating Densities
Plating Densities between 60,000-80,000 Optimal
At these densities there was the least variation in mean firing rates. This data shows as the density increased the cells moved towards firing in synchronicity.
Figure: Difference in Mean Motor Neurons Firing Rates vs Plating Densities

The demand for using these motor neurons for neuromuscular diseases drug discovery has been brisk and growing. Should you have question on how they would work for your unique applications, do not hesitate to contact me directly @ 612-801-1007 or pshuster@neuromics.com. Pete Shuster, CEO and Owner, Neuromics

Wednesday, June 03, 2015

Neuromics' Neurononal Cultures in Action

Drug Discovery and Tox Assay Publications

Our Primary Human, Rat and Mouse Neurons are widely used and frequently cited in publications. Here's a pub hot of the presses referencing use of our e18 Rat Cortical Neurons to study the 
EPO-like cytoprotective effects cultures of these cells: James L. Miller, Timothy J. Church, Dmitri Leonoudakis, Karen Lariosa-Willingham, Normand L. Frigon, Connie S, Tettenborn, Jeffrey R. Spencer, and Juha Punnonen. Discovery and Characterization of Nonpeptidyl Agonists of The Tissue-Protective Erythropoietin Receptor. Molecular Pharmacology. May 27, 2015 mol.115.098400

...Cells were isolated from micro-surgically dissected embryonic day 18 rat cortices that were obtained from Neuromics (Edina, MN), and cultures were prepared according to the supplier's protocol.

Image: Neuromics' Cortical Neurons @ Day 6 in Culture.

I will new and unique applications for our neurons, astroglia and neural progenitors here. If you have questions, do not hesitate to contact me @ 612-801-1007 or pshuster@neuromics.com. Pete Shuster, CEO and Owner, Neuromics

Friday, May 29, 2015

Neuromics' Stem Cell Markers

Potent, Proven and Published

We have a growing parade of Publications referencing use of our Stem Cell Markers. They have proven to be excellent for assays using our hNP1™ Human Neural Progenitor Kits and Human Mesenchymal Stem Cells (hMSCs),

Here's a recent reference highlighting use of our Nucleostemin Antibody: Zhe Ding and He Huang. Mesenchymal stem cells in rabbit meniscus and bone marrow exhibit a similar feature but a heterogeneous multi-differentiation potential: superiority of meniscus as a cell source for meniscus repair. BMC Musculoskeletal Disorders (2015) 16:65 DOI 10.1186/s12891-015-0511-8. ...After removing the medium, the cells were washed with PBS once. MMSCs and BMSCs were fixed with 4% paraformaldehyde in PBS for 30 min at room temperature and treated with 0.1% Triton X-100 for 30 min for Nanog and nucleostemin staining. After washing the cells with PBS, either mouse anti-Nanog (1:350, Santa Cruz Biotechnology, Inc., cat. # SC-33759, Santa Cruz, CA) or goat antinucleostemin (1:400, Neuromics, Cat. # GT15050, Edina, MN)...

Figure: Expression of Nucleostemin for BMSCs (E) and MMSCs (F).
I will continue to post Stem Cell Marker success stories here.

Thursday, May 21, 2015

GFP Labeled Motor Neurons and MEA

Big Upcoming Webinar

We have been strategically partnering with ArunA Biomedical to improve how we serve Neuro-drug discovery and Neurotox research community. I am especially excited about how well are our GFP Labeled Mouse Neurons are working in many different and unique research applications. They have proved an important tool in the study of neuro-muscular diseases like ALS, Parkinson's and Multiple Sclerosis.
I am pleased to announce a coming Webinar: “GFP+ Motor Neurons: Development and in-vitro Functional Assessment” Wednesday June 10th, 11:30 AM EDT-Register Today!


Download Flyer. I will continue to post unique assays developed for our Astro-glial Neuron solutions.

Sunday, May 17, 2015

Proven Stem Cell Markers and Multiple Applications

More Bang for Your Buck!

Our Stem Cell Markers remain a growth engine for Neuromics. One of the reasons that you would want to check out offerings are that we have selected markers that can be used in multiple applications.

For example, many of our markers can be used for immunostaining assays to confirm your stem cells are expressing the correct proteins and then these calls can further characterized and purified by Flow Cytometry, Here's an example of  one of our Nestins being used for these two applications.
Figures: (A): Nestin is present in both cell lines, . (B) Corresponding validation by immunofluorescence analysis. (C) Quantitation of nestin intracellular antigen detection (n=3). Error bars indicate standard deviation. DOI: 10.1371/journal.pone.0068519 .

Here are Stem Cell Markers that are designed for Multiple Applications. If you can cover your required applications with one antibody, the net results is a big cost savings!
Name
Catalog #
Type
Species
Applications
Size
Price
GT15239
Sheep IgG
M
ICC; WB; FC; E
100 ug
$365
GT15145
Goat IgG
H; R
IHC; WB; FC; E
100 ug
$365
GT41003
Goat IgG
H
IHC; WB; E
100 ug
$250
GT15149
Goat IgG
H
IHC; WB; E
100 ug
$365
RA30008
Rabbit IgG
H
IHC; WB
50 ug
$425
CH15000
Chicken IgY
H; R
IHC; WB; E
100 ug
$365
MO15115
Mouse IgG
H
IHC; WB; E
500 ug
$325
RA25083
Rabbit IgG
B; Ca; Ch; H; M; Pr; R; Rb; Ze
ICC; IF; WB
100 ul
$265
GT15053
Goat IgG
H; R
ICC; IHC; WB; E
100 ug
$365
GT15166
Goat IgG
H
IHC; WB; E
100 ug
$365
MO20038
Mouse IgG
H
IHC; WB
100 ul
$195
GT15054
Goat IgG
H; R
ICC; IHC; WB; E
100 ug
$365
GT15167
Goat IgG
H
IHC; WB; E
100 ug
$365
GT15161
Goat IgG
H; R
IHC; WB; FC; IP; E
100 ug
$365
GT15229
Goat IgG
M; R
IHC; WB; E
100 ug
$365
GT15224
Goat IgG
H; M
IHC; WB; E
100 ug
$365
GT15244
Goat IgG
H; M
ICC; WB
100 ug
$365
RA25085
Rabbit IgG
H
IF; WB
100 ul
$355
RA18007
Rabbit IgG
H; M; Pr; R
IHC; WB
100 ul
$370
RA25012
Rabbit IgG
H; M
IHC; WB; FC
100 ul
$285
CH23021
Chicken IgY
H; M
IHC; WB
100 ul
$99
MO15088
Mouse IgG
H
IHC; FC
100 ug
$325
GT15190
Sheep IgG
H
IHC; WB; E
100 ug
$365
MO20006
Mouse IgG
H
IHC; WB
100 ul
$150
MO20007
Mouse IgG
H
IHC; WB
100 ul
$150
MO15077
Mouse IgG
H
IHC; FC
100 ug
$325
MO15087
Mouse IgG
H
FC; IHC
100 ug
$255
GT15233
Goat IgG
H
IHC; WB; FC; E
100 ug
$365
GT15162
Goat IgG
M; R
IHC; WB; E
100 ug
$365
GT15156
Goat IgG
H
IHC; WB; E
100 ug
$365
MO15072
Mouse IgG
H
IHC; FC
500 ug
100 ug
$325
$89
MO15073
Mouse IgG
H
IHC; FC; NB
100 ug
$325
MO15022
Mouse IgG
H
FC; IHC
100 ug
$325
GT15191
Goat IgG
H; R
IHC; WB; E
100 ug
$365
RA25091
Rabbit IgG
H; M
FC; ICC; IF; WB
100 ul
$295
GT30000
Goat IgG
H
IHC; WB; E
50 ug
$365
GT15222
Goat IgG
M
IHC; WB; E
100 ug
$365
GT15067
Goat IgG
M
IHC; WB; E
100 ug
$365
MO22113
Mouse IgG
B; H; M; P; R
IF; WB
100 ul
$295
GT15247
Goat IgG
H
FC; ICC; IHC; WB
100 ug
$365
MO15124
Rat IgG
M
FC; ICC; IHC; WB
100 ug
$265
GT15035
Goat IgG
M; R
IHC; WB; E
100 ug
$365
GT15025
Goat IgG
M; R
ICC; WB; E
100 ug
$365
GT15026
Goat IgG
M; R
IHC; WB; FC; E
100 ug
$365
MO27001
Mouse IgM
H
WB; IP; E
500 ug
$175
GT15093
Goat IgG
M; R
ICC; IHC; WB; E
100 ug
$365
GT15228
Goat IgG
H
IHC; WB; E
100 ug
$365
GT15217
Goat IgG
M
IHC; WB; E
100 ug
$365
MO15024
Rat IgG
M
IHC; WB; FC
100 ug
$255
MO15035
Mouse IgG
H
IHC; WB
100 ug
$255
GT15099
Goat IgG
H
ICC; WB
100 ug
$365
GT15176
Goat IgG
M
IHC; WB; E
100 ug
$365
GT15177
Goat IgG
M
IHC; WB; E
100 ug
$365
CH23011
Chicken IgY
H; M
ICC; IF; IHC; WB
200 ul
$265
MO15052
Mouse IgG
H; R
IHC; WB; E
100 ul
$255
RA22101
Rabbit IgG
Ca; H; M; R
ICC; IHC; WB
100 ul
$275
CH22102
Chicken IgY
H; M; Pr; R
ICC; IHC; WB
100 ul
$275
RA25071
Rabbit IgG
H
FC; ICC; IF; IHC
100 ul
$315
GT15186
Goat IgG
H
IHC; WB; E
100 ug
$365
GT15051
Goat IgG
H; M
ICC; WB
100 ug
$365
GT15171
Goat IgG
H
E; IHC; WB
100 ug
$365
RA25095
Rabbit IgG
H; M
ICC; IF; WB; IP
100 ul
$245
RA25039
Rabbit IgG
H; M; P
ICC; IF; IHC
500 ul
$350
RA14132
Rabbit IgG
H; M; R
IF; IHC; FC
100 ul
$350
CH22103
Chicken IgY
H; M; Pr; R
ICC; IHC; WB
50 ul
$295
GT15141
Goat IgG
H
IHC; WB; E
100 ug
$365
GT15216
Goat IgG
M
IHC; WB; E
100 ug
$365
MO15048
Rat IgG
H; M
ICC; WB; E
100 ug
$255
MO15049
Mouse IgG
H
ICC; IHC; WB; E
100 ug
$255
GT15116
Goat IgG
H
ICC; IHC; WB; E
100 ug
$365
GT15143
Goat IgG
H
IHC; WB; E
100 ug
$365
MO15012
Mouse IgG
H; Pr
FC; ICC; IHC
100 ug
$265
MO15056
Mouse IgG
M; R
FC; ICC; IHC
100 ug
$255
CH23001
Chicken IgY
H; M
ICC; IHC; WB
100 ul
$99
GT15114
Goat IgG
M; R
IHC; WB; E
100 ug
$365
CH23002
Chicken IgY
H; M
ICC; IHC; WB
100 ul
$99
GT15164
Goat IgG
H
IHC; WB; E
100 ug
$365
GT15231
Goat IgG
H; M
ICC; WB
100 ug
$365
CH22104
Chicken IgY
H; M; Pr; R
ICC; IHC; WB
50 ul
$275
MO22103
Mouse IgG
Ch; H; M; Pr; R
ICC; IHC; WB
100 ul
$225
CH22105
Chicken IgY
Ca; Ch; H; M; R
ICC; IHC; WB
100 ul
$275
MO22104
Mouse IgG
Ca; Ch; H; M; R
ICC; IHC; WB; E
100 ul
$275
CH22106
Chicken IgY
Ch; H; M; R
ICC; IHC; WB
100 ul
$275
MO22105
Mouse IgG
Ch; H; M; R
ICC; IHC; WB
100 ul
$225
CH22101
Chicken IgY
H; M; R
FC; IF
100 ul
$275
GT15159
Goat IgG
M
ICC; IHC; WB; E
100 ug
$365
GT15124
Goat IgG
R
IHC; WB; FC; E
100 ug
$365
RA19070
Rabbit IgG
H; R
IHC; WB
100 ug
$215
GT15050
Goat IgG
H; M; R
ICC; WB; E
100 ug
$365
RA19067
Rabbit IgG
M; R
IHC; WB
100 ul
$275
GT15052
Goat IgG
H; M
ICC; WB
100 ug
$365
GT15132
Goat IgG
H; M
IHC; WB; E
100 ug
$365
RA25081
Rabbit IgG
H; M; R
ICC; IP; IHC; WB
100 ul
$395
MO15001
Mouse IgM
H; M; R
IHC; FC
50 ug
$215
MO15002
Mouse IgM
H; M; R
FC; IHC
50 ug
$215
GT15095
Goat IgG
H; M
ICC; WB; E
100 ug
$365
MO15039
Mouse IgG
H
ICC; IHC; WB
100 ug
$255
GT15187
Goat IgG
H
IHC; WB; E
100 ug
$365
CH23008
Chicken IgY
H; M
ICC; IHC; WB
100 ul
$99
MO15102
Rat IgG
M; R
IF; IHC; WB; E
100 ug
$255
GT15215
Rabbit IgG
H; R
IHC; WB; FC; E
100 ug
$365
MO15051-100
Mouse IgG
H
ICC; FC
100 ug
$255
GT15002
Goat IgG
M; R
IHC; WB; E
100 ug
$365
GT15002B
Goat IgG
M; R
IHC; WB
50 ug
$395
GT15169
Sheep IgG
M
IHC; FC; E
100 ug
$365
GT15212
Sheep IgG
M
IHC; FC; E
100 ug
$365
GT15188
Goat IgG
H
E; ICC; WB
100 ug
$365
RA25022
Rabbit IgG
H; M; R
IHC; WB; IP
100 ug
$365
GT15160
Goat IgG
H
IHC; WB; E
100 ug
$365
GT15232
Goat IgG
H; M
ICC; WB
100 ug
$365
GT15219
Goat IgG
H; R
IHC; WB; E
100 ug
$365
RA30033
Rabbit IgG
B; Ch; H; M; P; R
IHC; WB; E
50 ug
$365
GT15192
Goat IgG
H; M; R
IHC; WB; E
100 ug
$365
GT15245
Goat IgG
H
ICC; WB; IP
100 ug
$365
GT15032
Goat IgG
M; R
ICC; WB; E
100 ug
$365
GT15208
Goat IgG
H
IHC; WB; E
100 ug
$365
MO15040
Mouse IgG
H
IHC; WB
100 ug
$255
GT15098
Goat IgG
H
IHC; WB; E
100 ug.
$375
RA25021
Rabbit IgG
H; M
ICC; IHC; WB
100 ul
$275
GT15119
Goat IgG
H
ICC; WB; E
100 ug
$365
RA19023
Rabbit IgG
H; M; Pr; R
IHC; WB
100 ug
$225
GT15207
Goat IgG
H
IHC; WB; E
100 ug
$365
GT15218
Goat IgG
H
IHC; WB; E
100 ug.
$365
GT15094
Goat IgG
H
ICC; WB; E
100 ug
$365
GT15209
Goat IgG
H; M
IHC; WB; E
100 ug
$365
RA25027
Rabbit IgG
H; M
ICC; WB; FC; IP
100 ul
$275
GT15240
Goat IgG
M
IHC; WB; E
100 ug
$365
RA18010
Rabbit IgG
M; R
IHC; WB
100 ul
$370
MO20000
Mouse IgG
H; R
IHC; WB
100 ul
$175
RA18032
Rabbit IgG
Ch; H; M; R
WB; IP
100 ul
$325
RA18033
Rabbit IgG
H; M; R
IF; WB; IP
100 ul
$325
MO15106
Mouse IgG
H; M; Pr; R
IHC; WB; FC; E
500 ug
$325
GT15073
Goat IgG
H
IHC; WB; E
100 ug
$345
GT15147
Goat IgG
H
IHC; WB; E
100 ug
$365
GT15148
Goat IgG
H
IHC; WB; E
100 ug
$365
GT15189
Goat IgG
H
ICC; WB; E
100 ug
$365
MO25035
Mouse IgM
H
ICC; IF; WB; FC
100 ul
$275
MO25034
Mouse IgM
H
IF; IP; IHC; WB
100 ul
$245
MO15013
Mouse IgG
H
ICC; IF; IHC; WB
100 ug
$265
CH23005
Chicken IgY
H; M
ICC; IHC; WB
100 ul
$99
MO20001
Mouse IgG
H; M; R
ICC; WB
100 ul
$200
MO22941
Mouse IgM
M; Pr; R
IHC; WB
100 ul
$350
CH23006
Chicken IgY
H; M
ICC; IHC; WB
100 ul
$99
SO25000
Sheep IgG
H; M; Pr; R
ICC; IF; IHC; WB
100 ul
$325
RA18026
Rabbit IgG
R
IF; IHC; WB; IP
100 ul
$335
CH23010
Chicken IgY
H; M
ICC; IHC; WB
100 ul
$99
CH22108
Chicken IgY
H; M; R
IHC; WB
100 ul
$275
GT15241
Sheep IgG
H; M
ICC; WB
100 ug
$365
GT15242
Goat IgG
H; M
ICC; IHC; WB
100 ug
$365

Should you ever have questions on any of our solutions, please contact me directly @ 612-801-1007 or pshuster@neuromics.com. Thank you. Pete Shuster, CEO & Owner, Neuromics