Neuromics' Human Brian Microvascular Endothelial Cells in Action

Fc-saxatilin inhibits VEGF-induced permeability by regulating claudin-5 expression in human brain microvascular endothelial cells (HBMVECs)

Neuromics' cells were at the heart of this study.

Highlights: 

Fc-saxatilin prevents VEGF-induced permeability in human brain microvascular cells (HBMVECs). 

Fc-saxatilin inhibits VEGF-induced Src and Fak phosphorylation in HBMVECs. 

Fc-saxatilin blocks the downregulation of claudin-5 expression by VEGF in HBMVECs.

Image: HMBECS in Culture

Protocol: Human brain microvascular endothelial cells (HBMVECs) were purchased from Neuromics (HEC02; Minneapolis, MN, USA). HBMVECs were maintained in ENDO-growth medium (MED001; Neuromics). 

Here's a link to the full study: https://www.sciencedirect.com/science/article/pii/S0026286219301177#!