In this study, the authors developed a 3D functional human microvascular network in a microfluidic device. The established model enables Neuromics GFP-labeled human umbilical vein endothelial cells to form vessel-like microtissues and have physiological functions which are closer to cells in human blood vessels. The perfusable microvasculature allows the delivery of nutrients, and oxygen, as well as flow-induced mechanical stimuli into the luminal space of the endothelium. The microflow effectively mimic the blood flow in human vessels.
This in-vivo like model is then used for toxicity assays-Yan Li, Qing-Meng Pi, Peng-Cheng Wang, Lie-Ju Liu, Zheng-Gang Han,Yang Shao, Ying Zhai, Zheng-Yu Zuo, Zhi-Yong Gong, Xu Yang and Yang Wu. Functional human 3D microvascular networks on a chip to study the procoagulant effects of ambient fine particulate matter. : RSC Adv., 2017, 7, 56108
Images: Microvascular network formation based on microfluidic 3D HUVEC culture. (A) Schematic diagram of a microfluidic device. (B) Schematic diagram of microvascular network formation based on microfluidic 3D HUVEC culture. (C) Schematic diagram of loading microparticles in microvascular networks. (D) Microscope image of HUVECs seeding in fibrin hydrogel. (E) Confocal microscope image of fluorescent microvascular networks.
Our human primary and stem cells are widely used and frequently published. We will continue to post relevant results from researchers using the cells here.
Posts
1 comment:
Hello everyone, I have been suffering from herpes virus since 2017. During the first year the OB was all over my body was type 1 and 2 was using famciclovir and valacyclovir to control the OBs. Was always feeling bad and needed a cure, went on web and saw about Chief Dr Lucky I saw a testimonies of someone who has been cured from genital warts and another with Cancer by Chief Dr Lucky so I wrote to Chief Dr Lucky telling him about my herpes virus he told me not to worry that i was going to be cured I was happy, well after all the procedures and remedy given to me by him, few weeks later i started experiencing changes all over me as assured by him. After some time i went to my doctor to confirm if i have been finally free from the virus oh it was real. hepatitis, genital wart, herpes/STDs and diabetes. you can email him on> chiefdrlucky@gmail.com or WhatsApp +2348132777335
Http://facebook.com/chiefdrlucky
Https://chiefdrluckyherbaltherapy.wordpress.com/
Post a Comment