Parkinson's Disease and the Striatum

Excellent Video
Researchers at the Karolinska Institute recently released a video outlining their findings regarding the root causes of Parkinson's.

Highlights

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Striatal sensory responses were studied by whole-cell recordings and optogenetics

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Dopamine (DA) depletion affects intrinsic and sensory properties in direct pathway neurons

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The encoding of bilateral tactile stimuli is impaired following DA depletion

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Administration of L-DOPA can correct sensory deficits caused by DA depletion.

for more see: https://doi.org/10.1016/j.neuron.2017.05.004

This study came to my attention the researchers used our Enkaphalin Antibody as a marker for the Dopaminergic Neurons. 

Image: Mouse striatum stained with D2 cell marker Enkephalin (RA14124) in green and with neuronal marker NeuN in red courtesy of Dr Heike Rebholz of City College of New York