Tuesday, January 11, 2011

SOX 17 Antibody that Rocks

Our SOX Antibodies are proving to be excellent Stem Cell Markers.  I would like to highlight a pub that references use of our Sox17  and a variety of other markers:

Pere Santamaria, Ignacio Rodríguez-Pizá, Xavier Clemente-Casares, Jun Yamanouchi, Lola Mulero-Perez, Trond Aasen, Angel Raya1 and Juan Carlos Izpisúa Belmonte. Turning Human Epidermis Into Pancreatic Endoderm. The Review of DIABETIC STUDIES 159 Vol. 7-No. 2-2010. DOI 10.1900/RDS.2010.7.158.

This pub references use of a variety of markers for showing differentiation of Human embryonic stem (hES)and induced pluripotent stem (iPS)into into pancreatic endoderm structures.

Real-time PCR and flow cytometry. A: Changes in the levels of different mRNAs in undifferentiated, and progressively differentiated, hES and iPS cells. A series of plates were cultured, as described in the materials and methods section. These were used for RNA extraction at the end of each differentiation stage, immediately prior to change in culture conditions (days 1, 3, 7, 10, and 13). B: Flow cytometric analysis of Sox17 and FoxA2 expression on cells harvested on day 3.

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