Substance-P Pub

We re-introduced our Substance P Whole Serum Guinea Pig and Substance P Purified-Guinea Pig Antibodies in 2008.

The feedback has been positive. Related to this, here's a recent reference:

Maureen S. Riedl, Stephen A. Schnell, Aaron C. Overland, Anne-Julie Chabot-Doré, Anna M. Taylor, Alfredo Ribeiro-Da-Silva, Robert P. Elde, George L. Wilcox, Laura S. Stone.
Coexpression of 2A-adrenergic and -opioid receptors in substance P-containing terminals in rat dorsal horn. The Journal of Comparative Neurology Volume 513 Issue 4, Pages 385 - 398 Published Online: 29 Jan 2009 Copyright © 2009 Wiley-Liss, Inc., A Wiley Company.

...guinea pig anti-SP (1:500; Neuromics Antibodies)...

Related Reagents:

Substance P-Rabbit
Substance P-Mouse
Neurokinin-1 (NK 1) (RA25001)
Neurokinin-1 (NK 1) Human (RA25003)
Neurokinin-3 (NK 3) (RA25001)
proNeurokinin B (proNKB or P2)
All Neuropeptides

Image: Immuofluorescent detection of Substance P in rat spinal cord dorsal horn (red fluorescence). DAPI (blue) was used as counter stain.

Rat Sensory Neurons and NK-1

A publication featuring our Neurokinin-1 (NK 1) Receptor just crossed my radar. It is authored by our friend, Dr. Matt Ramer.

Matt and his team at University of British Columbia study primary sensory nerve cells (neurons), which are responsible for the transmission of somatic (bodily) sensations such as touch, pain, hot, cold and so on from the periphery (skin, muscles and viscera) to the central nervous system (CNS, spinal cord and brain). His research extends to therapeutic potential of neurotrophins on regeneration in spinal cord injury and deafferentation pain.

In the past several years, he has generouly shared NT-3 and BDNF IHC data with us.

Here's a link to the publication:

Matt Ramer. Anatomical and functional characterization of neuropil in the gracile fasciculus. The Journal of Comparative Neurology. 10.1002/cne.21785.

Featured Reagent
Neurokinin-1 (NK 1) Receptor

Other Reagents to Consider:
Neurokinin-1 (NK 1) Human (RA25003)
Neurokinin-3 (NK 3) (RA25002)
Substance P (GP14103)
proNeurokinin B (RA25008)
All Neuropeptides
All Pain and Inflammation