Thursday, July 11, 2019

Rodent Cortical Astroglia

Controls for iPSC Derived Astroglia
We have been providing Neuroscientists rodent neurons and astroglia for many years. As a result, they have been frequently referenced in publications.

Here's a recent publications. In this study. the authors use our rat atsroglia as controls to determine homogeneity of iPSC derived cells.

P. Ni, H. Noh, Z. Shao, Q. Zhu, Y. Guan, J.J. Park, F. Arif, J.M. Park, C. Abani, C. Beaudreault, J.S. Park, E. Berry, A. Moghadam, P. Stanton, J.N. Hutchinson, B. Andrews, C. Faux, J. Parnevelas, L.M. Eisenberg, K. Park, V.Y. Bolshakov, S. Chung. (2019). Large-Scale Generation and Characterization of Homogeneous Populations of Migratory Cortical Interneurons from Human Pluripotent Stem Cells. Molecular Therapy-Methods & Clinical Development, 13:414-430. doi: 10.1016/j.omtm.2019.04.002.

Figure: CDP Treatment Enhances Migratory, Morphological, and Electrophysical Maturation (A) Analysis scheme for migration, arborization, and electrophysiology of cINs. (B) CDP treatment significantly increased the migration of generated iPSC cINs. cIN organoids were embedded in a Geltrex matrix at 9 weeks of differentiation with or without CDP treatment and analyzed for migration 7 days after embedding. White scale bars, 200 μm; yellow scale bars, 100 μm.

Need Cells? Just ask us. Rose Ludescher, Manager of Customer Satisfaction, rose@neuromics.com or 866-350-1500.

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