Monday, November 03, 2008

Power Trio of Pain Research Antibodies

I received a call from a customer asking if there were any publications referencing our rabbit Alpha 2a Adrenergic Receptor antibody. The resulting search found an article referencing excellent results using a trio of of our pain research antibodies. The research was conducted by our friend, Dr. Hui-Lin Pan and his team at University of Texas M.D. Anderson Cancer Center.

Shao-Rui Chen, Hao-Min Pan, Timothy E. Richardson, and Hui-Lin Pan. Potentiation of Spinal α2-Adrenoceptor Analgesia in Rats Deficient in TRPV1- Expressing Afferent Neurons. Published online 2007 March 24. doi: 10.1016/j.neuropharm.2007.03.009.

Images: Double immunofluorescence labeling showing α2C-AR- and TRPV1-immmunoreactivity in the spinal cord dorsal horn of one vehicle-treated and one RTX-treated rat. Representative confocal images showing α2C-AR- and VR1 C-terminus (TRPV1)-immunoreactivities in the spinal dorsal horn of one vehicle- and one RTX-treated rat. All images are single confocal optical sections. Scale bar, 100 μm. Inset: high-magnification images (scale bar = 10 μm) showing the distribution of α2C-AR- and TRPV1-immunoreactivity in the lamina I and II. Neuropharmacology. 2007 June; 52(8): 1624–1630.

Rabbit VR1 N-Terminus (TRPV1) is also referenced.

Related Reagents:
Alpha 2c
Pain and Inflammation Antibodies
Vision and Retina Antibodies

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