Showing posts with label VR1s. Show all posts
Showing posts with label VR1s. Show all posts

Thursday, October 18, 2018

TRP Antibodies

Some of the Best Available
Our TRP Channel Antibodies are widely used and frequently published.

Here's some data from researchers using on of our TRPV1 Antibodies.

Immunohistochemical expression of serum response factor in rat dorsal root ganglia. Dorsal root ganglia dissected from male Sprague-Dawley rat and imaged by confocal microscopy for (A) TRPV1 (blue), (B) AKAP (AKAP150, green), and (C) SRF (red), with colocalization represented in panel (D). White arrows indicate cells expressing all 3 proteins. Yellow line represents 50 μM in length; images are representative of 4 individual sections taken from 6 L4 to L6 DRG. (E) Venn diagram of coexpression between SRF (red circle), AKAP (AKAP150, green circle), and TRPV1 (blue circle). (F) Percentages of SRF coexpression with AKAP (AKAP150) or TRPV1 calculated from 8 randomly selected coverslips. DRG, dorsal root ganglia; SRF, serum response factor. Source Serum response factor mediates nociceptor inflammatory pain plasticity PAIN Reports3(3):e658, May/June 2018.
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Tuesday, August 05, 2008

TRPV1 Staining of Mouse DRG

This excellent staining comes to us courtesy of Katharina Zimmermann (Childrens Hospital Boston, Clapham Lab). This is some of the best staining we've seen using our VR1 C-Terminus (TRPV1) - mouse specific antibody.

Images: TRPV1 staining of C57BL/6 mouse dorrsal root ganglia. Tissues were stained using Alexa Fluor© 488 (Green) and counterstained with DAPI (blue).

cryosections, 10 microns thickness

Wednesday, June 04, 2008

TRPV1 Pub

Katrin Schnizler, Leonid P. Shutov, Michael J. Van Kanegan, Michelle A. Merrill, Blake Nichols, G. Stanley McKnight, Stefan Strack, Johannes W. Hell, and Yuriy M. Usachev. Protein Kinase A Anchoring via AKAP150 Is Essential for TRPV1 Modulation by Forskolin and Prostaglandin E2 in Mouse Sensory Neurons. J. Neurosci., May 2008; 28: 4904 - 4917 ; doi:10.1523/JNEUROSCI.0233-08.2008

......anti-TRPV1 antibody (catalog #RA14113; Neuromics, Edina, MN) and 30 mul of prewashed protein-A...mm NaCl). Probing was done using the Neuromics anti-TRPV1 antibody (1:500 dilution...with other TRPV1 antibodies either from Neuromics (N-terminus rabbit anti-TRPV1) or from......