Showing posts with label Kappa Opioid Receptor Antibodies. Show all posts
Showing posts with label Kappa Opioid Receptor Antibodies. Show all posts

Sunday, January 24, 2016

More and More OR Pubs

Potent, Proven and Frequently Published

Many labs have used our Opioid Receptor antibodies over the past 10+ years. We are grateful for the many publications and testimonals referencing successful use of these antibodies.

Here's a sampling of more recent publications: Wendy M. Walwyn, Wenling Chen, Hyeyoung Kim, Ani Minasyan, Helena S. Ennes, James A. McRoberts, and Juan Carlos G. Marvizón. Sustained Suppression of Hyperalgesia during Latent Sensitization by μ-, δ-, and κ-opioid receptors and α2A Adrenergic Receptors: Role of Constitutive Activity. The Journal of Neuroscience, 6 January 2016, 36(1): 204-221; doi: 10.1523/JNEUROSCI.1751-15.2016
...probed with antibodies to MOR (RA10104; Neuromics), p-Ser375-MOR (pMOR, RA18001; Neuromics) and p-Tyr416-Src family kinase (pSFK...serine-phosphorylated MOR (p-Ser375-MOR, RA18001; Neuromics) and a different MOR antibody (RA10104...
Jan Fraessdorf, Markus W. Hollmann , Iris Hanschmann, André Heinen, Nina C. Weber, Benedikt Preckel, Ragnar Huhn. Role of Endogenous Opioid System in Ischemic-Induced Late Preconditioning. Published: July 30, 2015DOI: 10.1371/journal.pone.0134283.
...Antibodies for μ-OR and δ-OR were purchased from Neuromics (Minneapolis, USA)...
Ying-Biao Chen, Fen-Sheng Huang, Ban Fen, Jun-Bin Yin, Wei Wang and Yun-Qing L nhibitory effects of endomorphin-2 on excitatory synaptic transmission and the neuronal excitability of sacral parasympathetic preganglionic neurons in young rat. Journal Name: Frontiers in Cellular Neuroscience, ISSN: 1662-5102, Article type: Original Research Article,Received on: 02 Apr 2015, Accepted on: 12 May 2015, Provisional PDF published on: 12 May 2015.
... guinea pig antiserum against MOR (1:1000, GP10106, Neuromics, Edina, Minnesota, USA)...
Sherika N. Smith, Candler Paige, Kandy T. Velazquez, Terika P. Smith, Srinivasa N. Raja, Steven P. Wilson, Sarah M. Sweitzer. Injury-specific promoters enhance herpes simplex virus mediated gene therapy for treating neuropathic pain in rodents. doi:10.1016/j.jpain.2014.12.007
...: MOR (Neuromics, RA10104, 1:1000)...


Figure: MOR in primary sensory neuron and its terminals were decreased in neuropathic mice. (A, B) Western blot shows that MOR protein were markedly decreased in sciatic nerve (A) and hindpaw skin (B) on day 7 after nerve injury when compared with sham-operated mice. The ratio of MOR/GAPDH in sham mice was set at 1 for quantifications. Zhou et al. Molecular Pain 2014, 10:51 http://www.molecularpain.com/content/10/1/51

We will continue to post information on our ORs.


Thursday, December 24, 2009

Opioid Receptors and Depression

Tricyclic antidepressants (TCAs) have been reported to interact with the Opioid Receptor system, but their pharmacological activity at opioid receptors has not yet been elucidated.

We would like to share a recent publications that sheds more light on the mystery. Our purified rabbit ployclonal phosphoERK1/2 Antibody is also referenced.

Pierluigi Onali, Simona Dedoni and Maria C. Olianas. Direct Agonist Activity of Tricyclic Antidepressants at Distinct Opioid Receptor Subtypes. JPET January 2010 vol. 332 no. 1 255-265 .

At the cloned μ-opioid receptor, TCAs showed low affinity and no significant agonist activity. These results show that TCAs differentially regulate opioid receptors with a preferential agonist activity on either δ or κ subtypes and suggest that this property may contribute to their therapeutic and/or side effects.

Related Reagents:
phosphoERK1/2 (Rabbit MAb)
Immune Response Research Antibodies
Immune Response Research Proteins
Neurotrophins and Growth Factor Antibdodies
Neurotrophin Proteins
Pain and Inflammation Research Antibodies

Friday, January 23, 2009

Opioid Receptor Antibodies that Rock

We have Opioid Receptor Antibodies that work hard for our customers.

They are extensively referenced. We feature select publications and are pleased to feature the latest referencing staining of mouse neurons using our Kappa Opioid Receptor.

...Dominika Labuz, Yvonne Schmidt, Anja Schreiter, Heike L. Rittner, Shaaban A. Mousa and Halina Machelska. Immune cell–derived opioids protect against neuropathic pain in mice. J. Clin. Invest. doi:10.1172/JCI36246. Copyright © 2009, The American Society for Clinical Investigation...
...κ-opioid receptor (1:800, Neuromics)...

All Opioid Receptor Publications-Mu, Kappa and Delta

Published Reagents:
Mu Opioid Receptor-Rabbit
Mu Opioid Receptor-Guinea Pig
Delta Opioid Receptor 358-372
Kappa Opioid Receptor

Related Reagents:
Opioid Receptors
All Pain and Inflammation