Introducing our Prostate Cancer Cells Lines

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Neuromics is pleased to introduce many of the top human prostate cancer cell lines to our already expansive selection of cell offerings. To complement the DU 145 cells we added earlier this year, Neuromics is now offering VcaP, LNCaP, and PC-3 cells to complete our catalog of human prostate cancer cell lines.

Image: VcaP cells in culture.

VCaP cells are known for their high androgen receptor and PSA expression. Unlike most other prostate cancer cell lines, LNCaP cells are highly sensitive to androgens and have a low tumorigenicity. Meanwhile, PC-3 cells are noted for their high metastatic potential along with their insensitivity to androgens and fibroblast growth factors. Lastly, DU 145 cells are not hormone-sensitive and do not express PSA.

Hypoxia Induced Angiogenesis and Tumor Microenvironment

Neuromic's HUVECS Used in Study

The tumor microenvironment is essential for promoting tumor physiology, structure, function, and growth. It is important that emerging therapies eradicate both tumors and related microenvironment. This important study focuses on the formation of these microenvironments: ERICA K. SCHNETTLER. THE FUNCTIONAL ROLE OF MIR-210 IN HYPOXIA-INDUCED ANGIOGENESIS. A DISSERTATION SUBMITTED TO THE FACULTY OF THE UNIVERSITY OF MINNESOTA. FEBRUARY 2017...Primary Human umbilical vein endothelial cells (HUVEC) were purchased from Lonza (Basel, Switzerland) and Neuromics (Edina, MN)...

Figure: miR-210 sensitizes HUVECs to bFGF induced tube formation. (A)Representative images of HUVEC tube formation are shown at 10X magnification. Cells were treated with miR-210 or sc-miR, serum starved, and then plated on a Geltrex (reduced growth factor) layer in the presence or absence or bFGF to stimulate tube formation. (B) Histogram represents quantification of total tube length, number of nodes, and junctions in the tube formation assay described in A. Analysis done with ImageJ Angiogenesis Analyzer plugin.

We will continue to post our updates our primary Human Endothelial Cells as they develop.

Need Cells From Diseased Donors?

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Some of our customers have expressed the need for Cells that have the phenotype of a given disease. This is especially true for researchers doing drug discovery for neuro-diseases like Alzheimer's and Parkinson's.

Deriving "hard to find" cells from tissue is one of our cornerstones.

If you have need for any type of human cell(s), give us a shot. I can be reached at 612-801-1007 or pshuster@neuromics.com. Thank you. Pete Shuster,CEO and Owner, Neuromics.