New Neuronal Markers

Check Them Out!
We continue to add new antibodies. Many are additions to our frequently used and widely published Neuron-Glial Markers.

Image: Immunofluorescent analysis of cortical neuron-glial cell culture from E20 rat stained with mouse mAb to GAP43, MO22170, dilution 1:1,000, in red, and costained with chicken pAb to MAP2, dilution 1:10,000, in green. The blue is DAPI staining of nuclear DNA. GAP43 antibody labels protein expressed in the axonal membrane of the neuronal cells, while the MAP2 antibody stains dendrites and perikarya of neurons.

Name	Species	Applications
Aurora A/B Kinase	Human, Mouse, Rat	ICC, WB, IHC, IF
Aurora B Kinase	Human, Mouse, Rat	ICC, WB, IHC, IF
Beta-Tubulin	Human, Mouse, Rat, Primate	ICC, WB, IHC, IF
DJ1/Park7 Polyclonal Rabbit Antibody	Human, Mouse, Rat	ICC, WB, IF
Fibrillarin	Human, Mouse, Rat	ICC, WB, IHC, IF
Galectin-3 Rabbit Polyclonal Antibody	Human, Mouse, Rat	ICC, WB, IF
GAP43	Human, Mouse, Rat	ICC, WB, IHC, IF
GAP43 (IgG)	Human, Mouse, Rat	ICC, WB, IHC, IF
HSP60 (Heat Shock Protein 60)	Human, Mouse, Rat	ICC, WB, IHC, IF
IBA1 Polyclonal Rabbit Antibody	Human, Mouse, Rat	ICC, WB, IHC, IF
Ki67	Human	ICC, WB, IF
Nestin	Human, Mouse, Rat	ICC, WB, IHC, IF
Nsp1p		ICC, WB, IHC, IF
OPA1	Human, Mouse, Rat	ICC, WB, IHC, IF
Pdi1p		WB, IP, IF
Secretagogin Polyclonal Chicken Antibody	Human, Mouse, Rat, Bovine	ICC, WB, IF
Vimentin	Human, Rat	ICC, WB, IHC, IF

All our products are tested, characterized and research ready.

Electrical Preconditioning of Stem Cells

Cool Science

The ability to manipulate hNPCs via a conductive scaffold creates a new approach to optimize stem cell-based therapy and determine which factors (such as VEGF-A) are essential for stroke recovery: Paul M. Georgea, Tonya M. Blissb, Thuy Huab, Alex Leed, Byeongtaek Oh, Alexa Levinson, Swapnil Mehta, Guohua Sun, Gary K. Steinberg. Electrical preconditioning of stem cells with a conductive polymer scaffold enhances stroke recovery. doi.org/10.1016/j.biomaterials.2017.07.020...anti βIII-tubulin (1:500, Neuromics, Edina, MN)...

Image: Neural progenitors were labeled with anti-rat Nestin polyclonal antibody (Cat#:GT15114) and stained with conjugated donkey anti-goat secondary anti-body (green). Differentiated neurons were labeled with neuron-specific mouse anti-β-III tubulin/ Tuj1-(Cat#MO15013 monoclonal antibody (red). Nuclei were stained with DAPI (blue).

We have excellent Stem Cell Differentiation Markers. Check them out.

Modeling HIV Latency

Generation of Infected Neurons
Researchers have developed a Neuronal Cell Line for the study of HSV-1 infection in humans. This line was developed by terminally differentiating human embryonic stem cells to neurons.

Our mouse monoclonal nestin antibody was used as a marker for the neural progenitor phase of this differentiation. Aldo Pourchet, Aram S. Modrek, Dimitris G. Placantonakis, Ian Mohr and Angus C. Wilson. Modeling HSV-1 Latency in Human Embryonic Stem Cell-Derived Neurons. Pathogens 2017, 6(2), 24; doi:10.3390/pathogens6020024.

Image:  In vitro derivation of human neural stem cells by differentiation of the Hes5::GFP human embryonic stem cell line. (A) Schematic showing the multistep neural induction protocol. TGFβi stands for TGF-β receptor I inhibitor (B) Bright field image of human embryonic stem cell (hESC) colonies cultured on mouse embryonic fibroblasts prior to reaching confluence. (C) Bright field image of rosette NSCs derived from dissociated hESC colonies cultured in neural induction media. (D) Phase contrast and indirect immunofluorescence images of NSC cultures grown on poly-l-ornithine/laminin-coated dishes in neural stem cell media and probed with an antibody against nestin, a neural stem cell marker. Nuclei were visualized with DAPI.

We will continue to post publications referencing use of our solutions.

Proven Stem Cell Markers and Multiple Applications

More Bang for Your Buck!

Our Stem Cell Markers remain a growth engine for Neuromics. One of the reasons that you would want to check out offerings are that we have selected markers that can be used in multiple applications.

For example, many of our markers can be used for immunostaining assays to confirm your stem cells are expressing the correct proteins and then these calls can further characterized and purified by Flow Cytometry, Here's an example of  one of our Nestins being used for these two applications.

Figures: (A): Nestin is present in both cell lines, . (B) Corresponding validation by immunofluorescence analysis. (C) Quantitation of nestin intracellular antigen detection (n=3). Error bars indicate standard deviation. DOI: 10.1371/journal.pone.0068519 .

Here are Stem Cell Markers that are designed for Multiple Applications. If you can cover your required applications with one antibody, the net results is a big cost savings!

Name	Catalog #	Type	Species	Applications	Size	Price
5T4	GT15239	Sheep IgG	M	ICC; WB; FC; E	100 ug	$365
ACE/CD143	GT15145	Goat IgG	H; R	IHC; WB; FC; E	100 ug	$365
Activin RIA	GT41003	Goat IgG	H	IHC; WB; E	100 ug	$250
Activin RIIA	GT15149	Goat IgG	H	IHC; WB; E	100 ug	$365
BAX	RA30008	Rabbit IgG	H	IHC; WB	50 ug	$425
BDNF	CH15000	Chicken IgY	H; R	IHC; WB; E	100 ug	$365
BDNF	MO15115	Mouse IgG	H	IHC; WB; E	500 ug	$325
Bmi1	RA25083	Rabbit IgG	B; Ca; Ch; H; M; Pr; R; Rb; Ze	ICC; IF; WB	100 ul	$265
BMP-2/4	GT15053	Goat IgG	H; R	ICC; IHC; WB; E	100 ug	$365
BMP-3b/GDF-10	GT15166	Goat IgG	H	IHC; WB; E	100 ug	$365
BMP-4	MO20038	Mouse IgG	H	IHC; WB	100 ul	$195
BMP-5	GT15054	Goat IgG	H; R	ICC; IHC; WB; E	100 ug	$365
BMP-6	GT15167	Goat IgG	H	IHC; WB; E	100 ug	$365
BMP-8	GT15161	Goat IgG	H; R	IHC; WB; FC; IP; E	100 ug	$365
BOC	GT15229	Goat IgG	M; R	IHC; WB; E	100 ug	$365
Brachyury	GT15224	Goat IgG	H; M	IHC; WB; E	100 ug	$365
Brg1	GT15244	Goat IgG	H; M	ICC; WB	100 ug	$365
c-Myc	RA25085	Rabbit IgG	H	IF; WB	100 ul	$355
phospho-CaMKII (Thr286)	RA18007	Rabbit IgG	H; M; Pr; R	IHC; WB	100 ul	$370
CD11b/c (OX-42)	RA25012	Rabbit IgG	H; M	IHC; WB; FC	100 ul	$285
CD11b (OX-42)	CH23021	Chicken IgY	H; M	IHC; WB	100 ul	$99
CCR1/CD191	MO15088	Mouse IgG	H	IHC; FC	100 ug	$325
CD31/PECAM-1	GT15190	Sheep IgG	H	IHC; WB; E	100 ug	$365
CD43 (Clone MT1)	MO20006	Mouse IgG	H	IHC; WB	100 ul	$150
CD44 Variant 3	MO20007	Mouse IgG	H	IHC; WB	100 ul	$150
CCR5	MO15077	Mouse IgG	H	IHC; FC	100 ug	$325
CCR6	MO15087	Mouse IgG	H	FC; IHC	100 ug	$255
CDCP1/CD138	GT15233	Goat IgG	H	IHC; WB; FC; E	100 ug	$365
CDO	GT15162	Goat IgG	M; R	IHC; WB; E	100 ug	$365
CXCL8/IL-8	GT15156	Goat IgG	H	IHC; WB; E	100 ug	$365
CXCR1/IL-8 RA	MO15072	Mouse IgG	H	IHC; FC	500 ug 100 ug	$325 $89
CXCR2/IL-8 RB	MO15073	Mouse IgG	H	IHC; FC; NB	100 ug	$325
CXCR4	MO15022	Mouse IgG	H	FC; IHC	100 ug	$325
Chordin	GT15191	Goat IgG	H; R	IHC; WB; E	100 ug	$365
Cripto1	RA25091	Rabbit IgG	H; M	FC; ICC; IF; WB	100 ul	$295
Dkk-1	GT30000	Goat IgG	H	IHC; WB; E	50 ug	$365
Dkk-2	GT15222	Goat IgG	M	IHC; WB; E	100 ug	$365
Desert Hedgehog	GT15067	Goat IgG	M	IHC; WB; E	100 ug	$365
Doublecortin/DCX	MO22113	Mouse IgG	B; H; M; P; R	IF; WB	100 ul	$295
Endoglin/CD105	GT15247	Goat IgG	H	FC; ICC; IHC; WB	100 ug	$365
Endoglin/CD105	MO15124	Rat IgG	M	FC; ICC; IHC; WB	100 ug	$265
EphA4	GT15035	Goat IgG	M; R	IHC; WB; E	100 ug	$365
Ephrin-A2	GT15025	Goat IgG	M; R	ICC; WB; E	100 ug	$365
Ephrin-B2	GT15026	Goat IgG	M; R	IHC; WB; FC; E	100 ug	$365
FGF-2	MO27001	Mouse IgM	H	WB; IP; E	500 ug	$175
FGF R5 beta	GT15093	Goat IgG	M; R	ICC; IHC; WB; E	100 ug	$365
FGF-9	GT15228	Goat IgG	H	IHC; WB; E	100 ug	$365
Frizzled 4/CD344	GT15217	Goat IgG	M	IHC; WB; E	100 ug	$365
gp130/CD130	MO15024	Rat IgG	M	IHC; WB; FC	100 ug	$255
GATA-1	MO15035	Mouse IgG	H	IHC; WB	100 ug	$255
GATA-2	GT15099	Goat IgG	H	ICC; WB	100 ug	$365
GDF-3	GT15176	Goat IgG	M	IHC; WB; E	100 ug	$365
GDF-5	GT15177	Goat IgG	M	IHC; WB; E	100 ug	$365
GFAP	CH23011	Chicken IgY	H; M	ICC; IF; IHC; WB	200 ul	$265
GFAP	MO15052	Mouse IgG	H; R	IHC; WB; E	100 ul	$255
GFAP	RA22101	Rabbit IgG	Ca; H; M; R	ICC; IHC; WB	100 ul	$275
GFAP	CH22102	Chicken IgY	H; M; Pr; R	ICC; IHC; WB	100 ul	$275
GPR49	RA25071	Rabbit IgG	H	FC; ICC; IF; IHC	100 ul	$315
HNF-3beta/FoxA2	GT15186	Goat IgG	H	IHC; WB; E	100 ug	$365
Islet-1	GT15051	Goat IgG	H; M	ICC; WB	100 ug	$365
Jagged1	GT15171	Goat IgG	H	E; IHC; WB	100 ug	$365
JARID2	RA25095	Rabbit IgG	H; M	ICC; IF; WB; IP	100 ul	$245
Ki67	RA25039	Rabbit IgG	H; M; P	ICC; IF; IHC	500 ul	$350
c-Kit/CD117	RA14132	Rabbit IgG	H; M; R	IF; IHC; FC	100 ul	$350
MAP2 (Microtubule assoc. protein 2)	CH22103	Chicken IgY	H; M; Pr; R	ICC; IHC; WB	50 ul	$295
MOG	GT15141	Goat IgG	H	IHC; WB; E	100 ug	$365
Mash1	GT15216	Goat IgG	M	IHC; WB; E	100 ug	$365
Mash1	MO15048	Rat IgG	H; M	ICC; WB; E	100 ug	$255
Musashi-1	MO15049	Mouse IgG	H	ICC; IHC; WB; E	100 ug	$255
Musashi-1	GT15116	Goat IgG	H	ICC; IHC; WB; E	100 ug	$365
NCAM-L1/CD171	GT15143	Goat IgG	H	IHC; WB; E	100 ug	$365
Nestin	MO15012	Mouse IgG	H; Pr	FC; ICC; IHC	100 ug	$265
Nestin	MO15056	Mouse IgG	M; R	FC; ICC; IHC	100 ug	$255
Nestin	CH23001	Chicken IgY	H; M	ICC; IHC; WB	100 ul	$99
Nestin	GT15114	Goat IgG	M; R	IHC; WB; E	100 ug	$365
Netrin-1	CH23002	Chicken IgY	H; M	ICC; IHC; WB	100 ul	$99
Netrin-4	GT15164	Goat IgG	H	IHC; WB; E	100 ug	$365
NeuroD1	GT15231	Goat IgG	H; M	ICC; WB	100 ug	$365
Neurofilament NF-H	CH22104	Chicken IgY	H; M; Pr; R	ICC; IHC; WB	50 ul	$275
Neurofilament NF-H, phosphylated	MO22103	Mouse IgG	Ch; H; M; Pr; R	ICC; IHC; WB	100 ul	$225
Neurofilament NF-L	CH22105	Chicken IgY	Ca; Ch; H; M; R	ICC; IHC; WB	100 ul	$275
Neurofilament NF-L	MO22104	Mouse IgG	Ca; Ch; H; M; R	ICC; IHC; WB; E	100 ul	$275
Neurofilament NF-M	CH22106	Chicken IgY	Ch; H; M; R	ICC; IHC; WB	100 ul	$275
Neurofilament NF-M	MO22105	Mouse IgG	Ch; H; M; R	ICC; IHC; WB	100 ul	$225
Neurofilament alpha-internexin/NF66	CH22101	Chicken IgY	H; M; R	FC; IF	100 ul	$275
Noggin	GT15159	Goat IgG	M	ICC; IHC; WB; E	100 ug	$365
Notch2	GT15124	Goat IgG	R	IHC; WB; FC; E	100 ug	$365
Notch3	RA19070	Rabbit IgG	H; R	IHC; WB	100 ug	$215
Nucleostemin	GT15050	Goat IgG	H; M; R	ICC; WB; E	100 ug	$365
Nurr1	RA19067	Rabbit IgG	M; R	IHC; WB	100 ul	$275
Oct3/4	GT15052	Goat IgG	H; M	ICC; WB	100 ug	$365
Olig2	GT15132	Goat IgG	H; M	IHC; WB; E	100 ug	$365
Olig2	RA25081	Rabbit IgG	H; M; R	ICC; IP; IHC; WB	100 ul	$395
Oligodendrocyte Marker O1	MO15001	Mouse IgM	H; M; R	IHC; FC	50 ug	$215
Oligodendrocyte Marker O4	MO15002	Mouse IgM	H; M; R	FC; IHC	50 ug	$215
Otx2	GT15095	Goat IgG	H; M	ICC; WB; E	100 ug	$365
Otx2	MO15039	Mouse IgG	H	ICC; IHC; WB	100 ug	$255
PDX1/IPF1	GT15187	Goat IgG	H	IHC; WB; E	100 ug	$365
PLP (Proteolipid Protein)	CH23008	Chicken IgY	H; M	ICC; IHC; WB	100 ul	$99
Patched homolog 1 (PTCH1)	MO15102	Rat IgG	M; R	IF; IHC; WB; E	100 ug	$255
Patched homolog 2 (PTCH2)	GT15215	Rabbit IgG	H; R	IHC; WB; FC; E	100 ug	$365
Prominin 2	MO15051-100	Mouse IgG	H	ICC; FC	100 ug	$255
Ret	GT15002	Goat IgG	M; R	IHC; WB; E	100 ug	$365
Ret Biotinylated	GT15002B	Goat IgG	M; R	IHC; WB	50 ug	$395
RGM-A	GT15169	Sheep IgG	M	IHC; FC; E	100 ug	$365
RGM-B	GT15212	Sheep IgG	M	IHC; FC; E	100 ug	$365
RUNX2	GT15188	Goat IgG	H	E; ICC; WB	100 ug	$365
S100B	RA25022	Rabbit IgG	H; M; R	IHC; WB; IP	100 ug	$365
S100B	GT15160	Goat IgG	H	IHC; WB; E	100 ug	$365
SLAIN1	GT15232	Goat IgG	H; M	ICC; WB	100 ug	$365
SMAD1	GT15219	Goat IgG	H; R	IHC; WB; E	100 ug	$365
SMAD3	RA30033	Rabbit IgG	B; Ch; H; M; P; R	IHC; WB; E	50 ug	$365
SMAD5	GT15192	Goat IgG	H; M; R	IHC; WB; E	100 ug	$365
Snail	GT15245	Goat IgG	H	ICC; WB; IP	100 ug	$365
Sonic Hedgehog	GT15032	Goat IgG	M; R	ICC; WB; E	100 ug	$365
SOX1	GT15208	Goat IgG	H	IHC; WB; E	100 ug	$365
SOX2	MO15040	Mouse IgG	H	IHC; WB	100 ug	$255
SOX2	GT15098	Goat IgG	H	IHC; WB; E	100 ug.	$375
SOX2	RA25021	Rabbit IgG	H; M	ICC; IHC; WB	100 ul	$275
SOX3	GT15119	Goat IgG	H	ICC; WB; E	100 ug	$365
SOX6	RA19023	Rabbit IgG	H; M; Pr; R	IHC; WB	100 ug	$225
SOX9	GT15207	Goat IgG	H	IHC; WB; E	100 ug	$365
SOX10	GT15218	Goat IgG	H	IHC; WB; E	100 ug.	$365
SOX17	GT15094	Goat IgG	H	ICC; WB; E	100 ug	$365
SOX21	GT15209	Goat IgG	H; M	IHC; WB; E	100 ug	$365
SSEA3	RA25027	Rabbit IgG	H; M	ICC; WB; FC; IP	100 ul	$275
Stella/Dppa3	GT15240	Goat IgG	M	IHC; WB; E	100 ug	$365
Synapsin	RA18010	Rabbit IgG	M; R	IHC; WB	100 ul	$370
Synaptophysin	MO20000	Mouse IgG	H; R	IHC; WB	100 ul	$175
TCF4 (C48H11)	RA18032	Rabbit IgG	Ch; H; M; R	WB; IP	100 ul	$325
TCF4 (C9b9)	RA18033	Rabbit IgG	H; M; R	IF; WB; IP	100 ul	$325
TGF beta 1	MO15106	Mouse IgG	H; M; Pr; R	IHC; WB; FC; E	500 ug	$325
TGF beta RII (type2)	GT15073	Goat IgG	H	IHC; WB; E	100 ug	$345
TIE1	GT15147	Goat IgG	H	IHC; WB; E	100 ug	$365
TIE2/CD202b	GT15148	Goat IgG	H	IHC; WB; E	100 ug	$365
TP63/TP73L	GT15189	Goat IgG	H	ICC; WB; E	100 ug	$365
TRA-1-60	MO25035	Mouse IgM	H	ICC; IF; WB; FC	100 ul	$275
TRA-1-81	MO25034	Mouse IgM	H	IF; IP; IHC; WB	100 ul	$245
Tuj 1 (Neuron-specific class III beta-tubulin)	MO15013	Mouse IgG	H	ICC; IF; IHC; WB	100 ug	$265
Tuj 1 (Neuron-specific class III beta-tubulin)	CH23005	Chicken IgY	H; M	ICC; IHC; WB	100 ul	$99
Tyrosine Hydroxylase	MO20001	Mouse IgG	H; M; R	ICC; WB	100 ul	$200
Tyrosine Hydroxylase	MO22941	Mouse IgM	M; Pr; R	IHC; WB	100 ul	$350
Tyrosine Hydroxylase	CH23006	Chicken IgY	H; M	ICC; IHC; WB	100 ul	$99
Tyrosine Hydroxylase	SO25000	Sheep IgG	H; M; Pr; R	ICC; IF; IHC; WB	100 ul	$325
phospho-Tyrosine Hydroxylase (Ser40)	RA18026	Rabbit IgG	R	IF; IHC; WB; IP	100 ul	$335
Vimentin	CH23010	Chicken IgY	H; M	ICC; IHC; WB	100 ul	$99
Vimentin	CH22108	Chicken IgY	H; M; R	IHC; WB	100 ul	$275
ZIC3	GT15241	Sheep IgG	H; M	ICC; WB	100 ug	$365
ZIC1	GT15242	Goat IgG	H; M	ICC; IHC; WB	100 ug	$365

Should you ever have questions on any of our solutions, please contact me directly @ 612-801-1007 or pshuster@neuromics.com. Thank you. Pete Shuster, CEO & Owner, Neuromics