Neuromics-3D Human Blood Brain Barrier!

Compound Penetration Study

  

Classification: Low permeability: Pe < 1.00 nm/s 

Moderate permeability: 1.00 < Pe < 10.0 nm/s 

High permeability: Pe > 10.0 nm/s 

* The signal responses of Atenolol , 

Sulpiride, and Cimetidine in receiver samples were undetectable.

For the convenience of calculation, 

1/300 of the measured peak area ratio (PAR) of the relevant AD (A>B Donor) 

samples were used as the PAR values of Atenolol , Sulpiride, and Cimetidine 

in receiver samples.

Check out the study-

https://www.neuromics.com/ittrium/reference/D8xf65cx8x1/BBB%20Penetration%20Data.pdf