Large Intestine Endothelial Cells

"Hard to Find", Potent and Pure

We asked one of our Large Biopharma users of our Large Intestine Endothelial cells, "Why Neuromics" and she told us, "It is hard to find these cells. Let alone ones that work as well as yours!"

Image: Large Intestine Endothelial Cells in Culture

We have many options for endothelial cells and pericytes. We also have the ability to microdissect out virtually any type of human cell. If you have need, just ask me. Direct cell: 612-801-1007 or pshuster@neuromics.com . Pete Shuster, CEO and Owner, Neuromics.

Human Endothelial Cells and Drug Discovery

Pure, Potent and Culture Ready
Alterations of endothelial cells and the vasculature play a central role in the pathogenesis of a broad spectrum of the most dreadful of human diseases, as endothelial cells have the key function of participating in the maintenance of patent and functional capillaries. This makes them a key component for Drug Discovery.

We are proud that Biotech and Biopharma Cos. are increasingly using our cells. We believe we represent the best options. Here're some of the cells currently available:

• Human Bladder Microvascular Endothelial Cells
• Human Cardiac Microvascular Endothelial Cells
• Human Dermal Lymphatic Microvascular Endothelial Cells
• Human Dermal Microvascular Endothelial Cells
• Human Glomerular Microvascular Endothelial Cells
• Human Large Intestine Microvascular Endothelial Cells
• Human Ovarian Microvascular Endothelial Cells
• Human Pancreatic Microvascular Endothelial Cells
• Human Prostate Microvascular Endothelial Cells
• Human Retinal Microvascular Endothelial Cells
• Human Synovial Microvascular Endothelial Cells
• Human Tonsil Microvascular Endothelial Cells

Microvascular Endothelial Cells in Action

Figures: HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching. A,B: Gene knockdown of EZH2 and SUZ12 was confirmed by qPCR. C,D: In HRMECs transfected with EZH2 siRNA in HG, miR-200b and VEGF were not significantly different from HG+control siRNA but decreased compared to NG+control siRNA. In HRMECs transfected with SUZ12 siRNA in HG, miR-200b was significantly increased with decreased levels of VEGF compared to HRMECs transfected with control siRNA, with levels similar to NG+control siRNA. E,F: Tube formation assay to measure endothelial branching. HRMECs transfected with HG+control siRNA demonstrated significantly increased branching compared to NG+control siRNA. Transfection of EZH2 siRNA did not reduce endothelial branching significantly compared to HG+control siRNA. However, transfection of SUZ12 siRNA significantly reduced endothelial branching compared to HG+control siRNA. 10.1371/journal.pone.0123987
We will keep you posted as we add more cell options.

Immortalized hMicroglia Now Available

In Stock and Ready to Culture!

One of our partners needed 10 million hMicroglia to assay TBI related auto-antibodies as key piece of there target discovery program. We were unable to find these cell available on the market. We decided to have them micro-dissected from human brain tissue and then immortalized.

This enabled us to answer the bell. We now make them available to you. We are offering 2000 USD off through August 31, 2016...only 2995 USD/1,000,000 immortalized cells.

Image: Immortalized Human Microglia in Culture.

Cells are cyropreserved and delivered frozen.

Questions? e-mail pshuster@neuromics.com or direct phone: 612-801-1007. Pete Shuster, CEO and Owner.

Need Human Cells? Ask Us!

From Astrocytes to Satellite CellsWe have many "hard to find" primary human cells in our catalog. We also have the ability to micro-dissect cells from both healthy and diseased tissue and make the related cells available in about 30 days. Here're are some of the currently available cells.

• Human Bladder Microvascular Endothelial Cells
• Human Cardiac Microvascular Endothelial Cells
• Human Dermal Lymphatic Microvascular Endothelial Cells
• Human Dermal Microvascular Endothelial Cells
• Human Glomerular Microvascular Endothelial Cells
• Human Large Intestine Microvascular Endothelial Cells
• Human Ovarian Microvascular Endothelial Cells
• Human Pancreatic Microvascular Endothelial Cells
• Human Prostate Microvascular Endothelial Cells
• Human Retinal Microvascular Endothelial Cells
• Human Synovial Microvascular Endothelial Cells
• Human Tonsil Microvascular Endothelial Cells
• Human Liver Sinusoidal Endothelial Cells
• Human Small Intestine Endothelial Cells

Human Breast CAFs

Images: aSMA Positive CAFs plus FC Data

We'll be posting more new cells here as they become available.

Pete Shuster-Owner and CEO--- pshuster@neuromics.com or 612-801-1007