Cancer Associated Fibroblasts provide the Matrices (ECMs) serve as cancer’s assistants as it spreads throughout the body.
Cancer cells (red) migrate on a CAF-derived extracellular matrix (green).
VANDERBILT UNIVERSITY; BEGUM ERDOGAN, DONNA WEBB
Unlike other ECMs, which normally form dense meshes, these arrange into parallel bundles forming the highway for tumor cell migration (The Scientist-December 15, 2015).
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